Oral anticoagulation throughout pregnancy in patients with mechanical heart valve prosthesis: Safe alternatives

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Anticoagulation treatment in patients with a mechanical heart valve

..................................................................................................................................................... iii Populärvetenskaplig sammanfattning ....................................................................................................... vii ABBREVIATIONS .........................................................................................

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eComment: Are low molecular weight heparin effective in mechanical valve prosthesis anticoagulation during pregnancy?

We read with great interest the report by Carnero-Alcazar and co-workers regarding the successful mechanical mitral valve replacement due to pros-thetic valve thrombosis in a first trimester pregnant woman w1x. Two percent of all pregnant women suffer from some kind of cardiac pathology. Although this incidence varies in different countries, cardiac disease is the leading cause of death in preg...

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Anticoagulation in pregnant women with mechanical heart valve prostheses.

OBJECTIVE To evaluate the outcome of pregnancy in women with mechanical heart valve prostheses in relation to the anticoagulant treatment used in the first trimester and the incidence of thrombotic and bleeding complications. METHODS 92 pregnancies in 59 women were followed between 1986 and 1997. In 31 pregnancies, oral anticoagulants were discontinued when pregnancy was diagnosed and subcuta...

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Oral anticoagulation in carriers of mechanical heart valve prostheses: experience of ten years.

BACKGROUND Published data suggest that rates of thromboembolism and bleeding, in patients with mechanical heart valve prostheses, can be very small by optimizing current anticoagulant therapy. OBJECTIVE To evaluate the occurrence of complications in patients with mechanical heart valve prostheses undergoing anticoagulant therapy optimized through specialized clinics. METHODS We studied the ...

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Oral Anticoagulation after Mechanical Heart Valve Replacement: Low Intensity Regimen can Make the Difference

Despite continuous improvement in the field, the ideal prosthetic heart valve remains to be developed. Patients with mechanical prosthetic heart valves are at risk of thrombosis and systemic embolism. The incidence rate of these serious complications is significantly reduced by lifelong Oral Anticoagulant Therapy (OAC) vitamin K antagonist (VKA) therapy. Despite its undeniable benefits, VKA the...

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ژورنال

عنوان ژورنال: Journal of the Saudi Heart Association

سال: 2013

ISSN: 1016-7315

DOI: 10.1016/j.jsha.2013.03.039